Question 17GS4GS3
CRISPR technology has rapidly advanced in recent years, with new tools and clinical breakthroughs. Highlight the recent developments in CRISPR-based gene editing technology applications. Discuss the opportunities and ethical challenges these advancements present for healthcare and society. (Answer in 250 words)
Main Body
CRISPR technology is a clinical breakthrough in gene - editing and modulation. Its benefits range from disease diagnosis to disease prevention in plants, animals and humans. Recent Developments in CRISPR-based gene editing technology: 1. CAR-T therapy for cancers [killing] T cellsT BHuman body (cancer detects & killing) 2. Tailored gene therapies: eg Sickle cell, Anemia therapies 3. Vaccine & Drug efficacy: (eg gene-editing from soil bacterium for effective Vaccines)
4. Early screening & Preventive Health care (eg cervical cancers) 5. Diagnosis and precision surgeries (eg Nano-Urea gold for sulphur eating bacteria) Opportunities for Healthcare and Society: 1. Curing genetic disordereg Mitochondria defects. 2. Empowering AIDS patients 3. Role in Bio-tech agriculture: eg pest - resistant, climate - resilient crop varieties 4. Preventive non - communicable diseases (eg cancer, Diabetes) 5. Tailored Health based on genetic make-up of patients: Health-IDs
Ethical Challenges: 1. Misuse for genetic make-over and racism 2. Against natural principles of selection & Variation 3. Lack of regulatory gap frameworks: eg Chinese doctor imprisoned for twin daughters gene-edible 4. Affordability: IPR on gene-tech 5. Risk on Human, Plant & Animal long term - One health
193 words1 paragraphs
Conclusion
There is need of ethical review committees, global governance and limited use of CRISPR without economic - social divide.
19 words
Diagram
CAR-T therapy process showing T cells → Red Blood cells → CAR-T therapy → Human body with cancer detection and killing
Topper
Simrandeep Kaur
AIR 14
Subject & Paper
GS4GS3
Topic
Science and Technology
Stem Cell Therapy
CRISPR Technology and Gene Editing
Writing Stats
212
Total words
1
Paragraphs
analytical
Tone