Socrates profound quote highlighted significance intelligence as to knowing nothing i.e. what we know is nothing compared to vast reservoir of knowledge.

Humans knowledge is limited by many factors like: (1) Limited memory capacity (2) Limited comprehending skills (3) Limited intellect But problem lies when we start assuming our limited knowledge as ultimate truth and start considering ourselves as ultimate intelligent. This leads to: (1) Intolerance towards after stops. (2) Our learning stops. (3) Ego developing

Socrates knew that acceptance of our limited knowledge is beginning of all wisdom. Galio Galili was convicted of heresy because he questioned established norm of geocentrism. It was because of this unacceptance of new knowledge that many scientists had to suffer initially. Socrates urge all to be always dissatisfied with hunger of knowledge. As it is said, 'It is better to be Socrates dissatisfied than a fool satisfied.'