2023 · Q21
In vertebrates, smooth endoplasmic reticulum in cells of which organ plays a crucial role in detoxification of toxic compounds?
general-sciencebiology-human-body
- ASpleen
- BIntestine
- CKidney
- DLiver
Explanation
The smooth endoplasmic reticulum is especially abundant in hepatocytes (liver cells), where its cytochrome P450 enzymes detoxify drugs, alcohol, poisons and metabolic wastes. The spleen, intestine and kidney do not possess this specialised detoxification machinery to a comparable degree. Hence the liver is the organ whose smooth ER plays the crucial detoxification role.